Disease: Hyperlipidemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ZMPSTE24 O75844 zinc metallopeptidase STE24 Enzyme 8.9E-16 0.517 0.731
ZGLP1 P0C6A0 zinc finger GATA like protein 1 0.39 0.512 0.808
YWHAZ P63104 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta Chaperone 0.94 0.475 0.846
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PLB1 Q6P1J6 phospholipase B1 1.7E-72 0.488 0.846
PLA2G7 Q13093 phospholipase A2 group VII Enzyme 5.3E-22 0.537 0.769
PLA2G2A P14555 phospholipase A2 group IIA Enzyme 9.7E-02 0.488 0.808
PLA2G1B P04054 phospholipase A2 group IB Enzyme 1.0E-10 0.468 0.846
PCSK9 Q8NBP7 proprotein convertase subtilisin/kexin type 9 Enzyme 2.7E-17 0.482 0.808
NR1I2 O75469 nuclear receptor subfamily 1 group I member 2 Nuclear receptor 7.3E-09 0.418 0.846
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885
MIR34A microRNA 34a 0.421 0.846
LPA P08519 lipoprotein(a) Enzyme 6.6E-89 0.444 0.769
LMNA P02545 lamin A/C 1.00 0.384 0.885
LIPC P11150 lipase C, hepatic type Enzyme 3.3E-07 0.585 0.654
LDLRAP1 Q5SW96 low density lipoprotein receptor adaptor protein 1 Signaling 6.5E-06 0.641 0.538
LDLR P01130 low density lipoprotein receptor 9.8E-24 0.449 0.885
LCAT P04180 lecithin-cholesterol acyltransferase Enzyme 8.1E-02 0.588 0.654
LAD1 O00515 ladinin 1 Cellular structure 1.8E-14 0.584 0.731
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885